Lifeworks Wellness Center is long recognized as one of the foremost natural health clinics in the US. At our Tampa Bay, Florida alternative medicine office we have been offering adrenal fatigue treatment and treatment for chronic fatigue syndrome for a long time and many of our patients have regained quality of life. Very few clinics offer natural adrenal fatigue treatment and so our patients fly in from all over the world because they simply can’t find clinics offering this treatment where they live. 
In the book, Dr Wilson examines the history of adrenal fatigue and discusses the reasons why this common problem has become largely overlooked by the allopathic medical profession. Dr Wilson provides a blueprint of the signs and symptoms of adrenal fatigue. He includes the tests for this dysfunction, their efficacy, specific and key supplementation facts, lifestyle modifications, and other significant strategies for recovering: “I decided to write this book for the person suffering from adrenal fatigue. It is designed to be a self-help book…. I write it with the hope that it will provide you with information, guidance, encouragement and tools you need to recover from this sometimes subtle, yet debilitating, health problem” (p xxii).
The contents of this website are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you have regarding a medical condition, and before undertaking any diet, dietary supplement, exercise, or other health program.
I was diagnosed with adrenal insufficiency by a progressive doctor. She meant well, but she missed the boat completely. For some people, the adrenal-busting cycle is caused by sleep disorders like sleep apnea. A healthy lifestyle alone (or supplements or other treatments that only target adrenals) can’t fix the hypothalamic-pituitary-adrenal axis dysruption caused by sleep apnea, and many of the systems will overlap. Nocturnal breathing pauses cause a stress response, elevating cortisol, increasing exhaustion, sabotaging sleep quality and all of the regenerative work our bodies are meant to do during sleep. For women, sleep apnea is likely to go undiagnosed, because doctors think it is so rare in women that they don’t usually consider it as a differential diagnosis (even in women with PCOS, who are known to have the same rate of sleep apnea as men). For young and slender women, sleep apnea is unlikely to be diagnosed until it has already caused long-standing biological changes, even if a woman has classic symptoms of sleep apnea like loud snoring, observed pauses in sleep breathing, and significant daytime sleepiness. Sleep dysruption is a form of chronic stress, so it can overlap with adrenal insufficiency, and treating sleep problems can be a big help to solving the adrenal problems.

A study published in the journal Psychiatry Research compared people in two different stress-management programs: one which involved meditation, one which didn’t. Those who meditated regularly were found to produce fewer stress hormones and low levels of stress-induced inflammation. Those who didn’t meditate, however, suffered much higher levels of stress hormones and inflammation. Follow this link for some of the scientifically proven benefits of meditation.

This extends to more than just lifestyle and dietary choices. Patients also need to identify and eliminate the sources of stress in their lives. This can often be difficult, but it is a necessary part of restoring their health. Unhealthy relationships, stressful jobs, family quarrels, money worries – these all need to be eliminated somehow. Often a patient will feel as though a huge weight has been lifted off their shoulders when these issues are fixed. As you would expect, that feeling also signifies a great deal of stress being taken off their adrenal glands and HPA axis too.

Nieman adds that even when patients come in “hell bent on having this diagnosis, when I listen to everything they have to say and validate the symptoms, but tell them, ‘I really don’t think your adrenal is actually failing, but I think some of your problems are reversible,’ I find that they accept [my point of view], and can give up on this adrenal fatigue diagnosis.”
Addressing one stressor at a time is generally the best way to approach this. Identifying what makes you happy and what stresses you is the easy part, then begins the difficult part of making the changes that you need to make. This will often require a significant adjustment in outlook. For example, if a high-paying job is damaging your health, can you step off the corporate ladder and return to a simpler, more fulfilling life? And if a relationship has been causing you emotional stress for years, do you have the courage to pull the plug and start again? All these are issues that can hopefully be addressed with the support of family, friends and perhaps even a good therapist too.
Hormones affect every function, organ and tissue in the body directly or indirectly. They react to each other as well as respond to conditions in the body in an intricate and highly sensitive balancing act. The adrenal glands work closely with the hypothalamus and the pituitary gland in a system known as the hypothalamus-pituitary-adrenal axis (HPA axis). (7)

The adrenal glands are 2 of the most powerful glands in the body. The adrenals produce a variety of hormones such as cortisol, DHEA and adrenaline. The adrenals modulate the body’s stress response, and are involved in numerous other biological functions including: digestive functions, inflammatory and anti-inflammatory responses, and the adrenal hormones interact with a simplex of other hormones.


Adrenals. Ahhhhhhh, how I wish I knew about these guys a decade ago before my doctor put me on steroids in my 20’s, which took away my pain but also destroyed my adrenals!!! It’s taken me over 10 years to build back my adrenals. So much fun. Let me tell you. This has become part of my life so I love learning new ways to heal myself and my adrenals have been anything but easy to heal. They’re tricky and they’re exhausting and you end up feeling depleted, tired and fed up most of the time. When I learned about adrenal fatigue treatment from my Functional/Integrative M.D.’s I was amazed at all the knowledge I found on how I could start to heal these babies, which were KEY for my thyroid health. You’ll never have an optimal thyroid if your adrenals are out of whack. So, let’s talk about what adrenals are and how you can make sure they’re in tip-top shape. As Susan Blum, M.D. (she was my 1st Functional MD) mentions in this article for Well&Good, 8 Signs You Have Adrenal Fatigue, “When there’s severe, chronic stress, the adrenal glands can stay in the ‘on’ position, making extra amounts of these stress hormones.”


Adrenals. Ahhhhhhh, how I wish I knew about these guys a decade ago before my doctor put me on steroids in my 20’s, which took away my pain but also destroyed my adrenals!!! It’s taken me over 10 years to build back my adrenals. So much fun. Let me tell you. This has become part of my life so I love learning new ways to heal myself and my adrenals have been anything but easy to heal. They’re tricky and they’re exhausting and you end up feeling depleted, tired and fed up most of the time. When I learned about adrenal fatigue treatment from my Functional/Integrative M.D.’s I was amazed at all the knowledge I found on how I could start to heal these babies, which were KEY for my thyroid health. You’ll never have an optimal thyroid if your adrenals are out of whack. So, let’s talk about what adrenals are and how you can make sure they’re in tip-top shape. As Susan Blum, M.D. (she was my 1st Functional MD) mentions in this article for Well&Good, 8 Signs You Have Adrenal Fatigue, “When there’s severe, chronic stress, the adrenal glands can stay in the ‘on’ position, making extra amounts of these stress hormones.”

In the early stages of adrenal dysfunction, cortisol levels are too high during the day and continue rising in the evening. This is called “hyperadrenia.” In the middle stages, cortisol may rise and fall unevenly as the body struggles to balance itself despite the disruptions of caffeine, carbs and other factors, but levels are not normal and are typically too high at night. In advanced stages, when the adrenals are exhausted from overwork, cortisol will never reach normal levels (“hypoadrenia”).


The diagnosis of Cushing syndrome (CS) requires evidence of cortisol hypersecretion. While serum cortisol levels fluctuate unpredictably and are strongly dependent on concurrent cortisol-binding globulin (CBG) levels, a 24-hour urine specimen integrates the cortisol production for an entire day and is not affected by CBG. Urinary cortisol reflects the portion of serum-free cortisol filtered by the kidney, and correlates well with cortisol secretion rate.
"You don’t know how much I appreciate your new book, The Adrenal Fatigue Solution. I have been undergoing unrelenting stress for 7 years. I haven’t understood why I cry, have so little energy, and am irritable all the time. Now I do, and I know how to cope. Your selfless efforts in gathering this book’s information are so generous. Thank you and God bless you. I love you for your help."
I have had anxiety/panic attacks for years and recently been through a lot of stress and have developed low blood pressure, dizziness and increased heart rate especially when walking around, and weakness, and sometimes episodes of dizziness where my blood pressure is high. I’m pretty sure this is adrenal insufficiency and I started taking 5,000mg vitamin C and started with 1tsp sole water and multi vitamin, and adrenal response supplement. I also follow a gluten free, soy free, dairy free with the exception of goat cheese. Is there anything else I can do to help?
Another oft-quoted piece of evidence against the existence of adrenal fatigue is Todd B. Nippoldt’s interview with Mayo Clinic, stating essentially the same concerns. (6) Again, it is stated that consistent levels of chronic stress have no effect whatsoever on the adrenals and the only true endocrine disorders are those caused by other diseases and direct damage to the adrenal glands.
Treatments for adrenal fatigue vary from using certain botanical medicines - which certainly will always play a major role, to using intravenous vitamin therapy. Usually this combination very quickly delivers results that both address the symptoms and nourish your adrenals back to optimal function. Additionally, patients usually need some blood sugar support and dietary changes to support stabilizing and decreasing insulin resistance while healing the adrenal glands.

Some people call the time when the "camel's back" finally breaks a "nervous breakdown." However, nerves really don't break down; adrenal glands do. A "nervous breakdown" is actually adrenal fatigue, or when the adrenal glands can't deal with the amount of stress they're given. Adrenal fatigue used to be rare, but is now all too common because of our lack of relaxation and other lifestyle factors, such as smoking, sleep deprivation, poor eating habits and excessive caffeine intake, as well as allergies.


Conventional medicine is truly wonderful at treating disease-state conditions. Unfortunately its focus on drugs also tends to suppress early-stage symptoms rather than treat their underlying causes. This can have the effect of delaying treatment until a disease state has developed. This is true in the case of adrenal fatigue cortisol testing. In the conventional standard of care, any cortisol level within a very broad range is considered normal, and anything outside that range indicates disease.

Oysters are packed with zinc! The trace mineral ratio between copper and zinc can help with healthy neurotransmitter function and adaptation to stress. Increased copper and decreased zinc has been shown to contribute to brain stress and anxiety. This superfood of the sea is a great way to balance the proper trace mineral ratio and your stress levels.

It is the observation of these scientists that suboptimal health, as an “in-between” status before disease, is a precursor to many health conditions and has been exacerbated by the culture shifts in the last several decades like Western lifestyle habits, pollution, poor diet and tobacco use. This study, intended to expand over subsequent years by large numbers, is an effort to legitimize some of the oft-ignored benefits of Traditional Chinese Medicine. (15)


Dr. Will Cole, leading functional-medicine expert, consults people around the world via webcam at www.drwillcole.com and locally in Pittsburgh. He specializes in clinically investigating underlying factors of chronic disease and customizing health programs for thyroid issues, autoimmune conditions, hormonal dysfunctions, digestive disorders, and brain problems.Dr. Cole was named one of the top 50 functional-medicine and integrative doctors in the nation and is the author of Ketotarian in which he melds the powerful benefits of the ketogenic and plant-based diets.
Mama, it is AS IF we are living parallel lives! 🙂 Minus the third precious child, farm, and homeschooling, this is me, SPOT ON. I am JUST FINISHING this book as well, after getting confirmation from the saliva test that my adrenals are “maladapted” (the calm before full-blown adrenal fatigue) and I’m trying like H-E double hockey sticks to modify my lifestyle (the # culprit – ongoing, compounded stress for YEARS, plus broken sleep for 18 months – nursing babes, and all!) to rebuild those reserves. I’m really looking forward to your series! Thank you for sharing your story! Lots of love! xo
What differentiates adrenal insufficiency from adrenal fatigue? More often than not, adrenal fatigue is modeled by an overabundance of cortisol, often at the “wrong” times, while adrenal insufficiency is a consistent inability to produce cortisol. They are related, though — many natural medicine practitioners, such as myself, see adrenal fatigue as a precursor to adrenal insufficiency. In fact, a description of adrenal insufficiency from the Cleveland Clinic states that “its early clinical presentation is most commonly vague and undefined, requiring a high index of suspicion.” (41)
Fish oil (EPA/DHA): There are a large number of benefits of supplementing with fish oil (or, for people on vegan or other plant-based diets, algal oil). Several of these include counteracting a number of adrenal fatigue-related symptoms and complications, such as diabetes, mental dysfunction, arthritis, immune system function, skin issues, weight gain and anxiety/depression.
I also promote quality sleep by turning off the TV, computer, and smartphone a few hours before bed (they can overstimulate the brain, block melatonin production, and hurt your quality of sleep). And I often eat an ounce or two of clean protein like organic turkey and 2 tablespoons of coconut oil before bed to balance out my blood sugar throughout the night.
After read this book I found that you could probably are dealing with the adrenal fatigue symptoms and you may not knowing, been tired, living with stress or having anxiety could be by this reason, here you can find the root cause and ways to test if you are dealing this this fatigue syndrome, one of the principal rules is to change your diet where you can find many solutions here.
Dr. Eric Wood is a licensed Naturopathic doctor with extensive clinical and teaching experience. He graduated from the Canadian College of Naturopathic Medicine with additional post graduate studies at the Benson Henry Institute of Mind Body Medicine at Harvard. Dr. Wood has worked in both private practice and consulting work, with experience in many different areas of Integrative and Mind Body Medicine. He has specialty training and expertise in the areas of oncology, infectious disease, Adrenal Fatigue and anti-aging medicine.
I have Hashimoto's and third stage adrenal fatigue. I've had Hashi's for 15 years. With Dr. Lam, I finally figured out that my issue is "adrenal fatigue syndrome," NOT just adrenal fatigue. I am actually taking Dr. Wilson's adrenal quartet, which has helped me immensely. (I also have Dr. Wilson's book.) Dr. Lam offers a similar adrenal fatigue regimen, but right now I'm not sure if I should try to switch from Dr. Wilson's adrenal supplements to Dr. Lam's - I may do so in the future.

The diagnosis of Cushing syndrome (CS) requires evidence of cortisol hypersecretion. While serum cortisol levels fluctuate unpredictably and are strongly dependent on concurrent cortisol-binding globulin (CBG) levels, a 24-hour urine specimen integrates the cortisol production for an entire day and is not affected by CBG. Urinary cortisol reflects the portion of serum-free cortisol filtered by the kidney, and correlates well with cortisol secretion rate.
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I've been disabled now for almost 10 years, but before that, I worked as an RN, BSN (with a certification in Infection Prevention) for over 30 years. I got my Bachelors in Nursing at a well-known University. Unfortunately, we, as students and as nurses, were indoctrinated with the belief that ONLY WESTERN ALLOPATHIC medicine was valid, and complementary and natural health were quacks. Some are, as well as some Western medicine doctors. It took me many many years to realize that our western medicine's practice of lab and radiological and other testings' means of diagnoses, followed by prescription medication as treatment, dictated by protocols and insurance companies, was doing more harm sometimes than good. I started believing in nutritional and natural means of helping my body heal itself was far better than medications in 2013. However, by that time, I was taking 10 prescription medications twice a day. In the beginning of 2016 I became so fatigued, I would fall back to sleep an hour after I slept 9 hours. I had SEVERE sleep apnea. I went to see an Endocrinologist, and ALL my results for Adrenal Insufficiency (Addison's Disease) were there- undetectable cortisol levels, undetectable epinephrine and norepinephrine in my 24-urine collections and blood tests. However, at the test that is called "The Gold Standard" for Addison's, my cortisol level went up 3 times the baseline after an injection of synthetic meds. So even with all these other abnormal tests and my overwhelming fatigue, I was told I didn't have Addison's and should come back for repeat tests in 6 months. If I sound angry, I am. I found an article on Wikipedia that said if your cortisol level goes up 3 times after that test, it indicates a pituitary or hypothalamus problem. The doctor "didn't think I had those issues". So, if YOU ARE LIKE ME, and you KNOW something is not right with you, and medical doctors ignore you, tell you it's all in your head, or you should just RELAX, READ THIS BOOK and others like it that deal with natural alternative healing. Use common sense in deciding what to try in helping your body recover health, but PLEASE TRY TO HELP YOURSELF and not totally rely on doctors who only give out pills, pills, and more pills. In fact, Dr. Wilson (who is NOT an MD, but is highly trained) writes a very vivid account of what western medicine has degenerated to right now. It is startling, and as an RN who worked in Quality and Risk, I know he is correct. Adrenal Fatigue is an epidemic today in the USA, where we live stressful lives and have stressful jobs. There is a test in the book that has been used to "diagnose" your tendency to have adrenal fatigue. And Dr. Wilson gives step by step actions we can take to "get our lives back", using nutrition, supplements, activities, and other natural remedies. He also tells about a simple saliva test for adrenal insufficiency or fatigue that the medical community refuses to accept. If you are sick and tired of being sick and tired, PLEASE CONSIDER buying and reading this book. If your doctor refuses to believe you are not well, help yourselves. Thank you for putting up with me if you read through this Long Review!!

Carbohydrates: While carbohydrates aren’t all bad for you, the inflammation they can cause is particularly problematic when experiencing adrenal fatigue. Many people crave carb-heavy foods when they’re stressed, which offer a momentary satisfaction but end up taxing the adrenal glands more. If you’re overwhelmed and stressed out, try kicking the gluten and starchy carbs for a period of time to see if that may regulate your tiredness and energy levels.
Your adrenals produce your stress hormones, which are super important for your metabolism and they totally effect your thyroid so it’s key to look at these glands when you’re dealing with any sort of thyroid issue. If you’re in that amped-up mode that causes you to feel stressed all the time (and you feel like you can’t turn it off), you’re headed for some degree of Adrenal Fatigue. In this state, your cortisol is chronically elevated or it’s high when it should be low (at night). Adrenal Fatigue is when your cortisol is chronically low when it should actually be elevated. Your production of stress hormones declines and leaves you with low adrenaline and low cortisol–feeling depleted.
Indeed, an article from a São Paulo university was released in 2016 with the title: “Adrenal fatigue does not exist: a systematic review.” According to this review, results of acceptable studies available to them at the time had “conflicting results” and could provide no definitive proof of the disease, nor diagnostic criteria or adrenal fatigue treatment. (4)
For anyone who has ever wondered why his or her doctor seems to know nothing about this syndrome, Dr. Wilson offers an answer. He does this by explaining the reasons why adrenal fatigue is so readily dismissed by most in the medical community. As he points out, there is always money involved in these considerations, and in the case of adrenal fatigue the money trail leads right to the pharmaceutical companies. At one time, adrenal fatigue was a well-known diagnosis, and patients actually received treatment for it. As the pharmaceutical industry grew larger and more politically connected, however, that diagnosis became rarer and rarer. Today, only the most severe forms of adrenal dysregulation – such as Addison’s disease – receive any serious recognition by doctors.
Now, when your cortisol gets too high, your pituitary and hypothalamus slow down and so they don’t let go of any stress hormones and your thyroid begins to slow down. Now your thyroid stops producing as much thyroid hormone, which causes your metabolism to slow down and you all of a sudden start gaining weight, even though you haven’t changed anything about what you eat or workout. You start to feel fatigued, foggy and unmotivated. Also, when your stress is high, you convert more T3 into Part III (read Part III to learn more about Reverse T3), which slows things down and halts your metabolism even more.
Proponents of the adrenal fatigue diagnosis claim this is a mild form of adrenal insufficiency caused by chronic stress. The unproven theory behind adrenal fatigue is that your adrenal glands are unable to keep pace with the demands of perpetual fight-or-flight arousal. As a result, they can't produce quite enough of the hormones you need to feel good. Existing blood tests, according to this theory, aren't sensitive enough to detect such a small decline in adrenal function — but your body is.
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